After creating a national circular vision in collaboration with Waternet and Rijkswaterstaat and comparing 20+ scenarios and case studies, we created a modular “Cicrular HUB” to handle anthropogenic waste. Circular HUBs effectively integrate into urban infrastructure and governance without causing disturbances at multiple scales. They provide context-specific and proven solutions that promote a symbiotic relationship among industrial, commercial, and residential sectors. These Circular HUBs have the capability to function autonomously within a single structure or as components of a network of interconnected HUBs that serve a wide variety of functions. Designing and managing Circular HUBs with a balance of technical and nature-based solutions enhances self-sufficiency and improves the economic performance, climate resilience, and biodiversity of buildings while promoting the health and well-being of the occupants. By harnessing innovative waste-to-value conversion techniques, we can transform discarded materials into marketable and sustainable commodities, fostering a circular economy that minimizes environmental impact and maximizes resource utilization.